Magnetic resonance imaging findings in corticobasal degeneration
Identifieur interne : 004D16 ( Main/Exploration ); précédent : 004D15; suivant : 004D17Magnetic resonance imaging findings in corticobasal degeneration
Auteurs : Juliane Winkelmann [Allemagne] ; Dorothee P. Auer [Allemagne] ; Christian Lechner [Allemagne] ; Gregor Elbel [Allemagne] ; Claudia Trenkwalder [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 1999-07.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Alien limb phenomenon, Basal Ganglia (pathology), Basal Ganglia (physiopathology), Basal Ganglia Diseases (pathology), Basal Ganglia Diseases (physiopathology), Basal ganglion, Body Image, Brain (vertebrata), Case study, Cerebral Cortex (pathology), Cerebral Cortex (physiopathology), Cerebral cortex, Cortical myoclonus, Corticobasal degeneration, Degeneration, Disease Progression, Evoked Potentials, Somatosensory (physiology), Exploration, Female, Follow-Up Studies, Human, Humans, Magnetic Resonance Imaging, Magnetic resonance imaging, Median Nerve (physiopathology), Middle Aged, Movement Disorders (pathology), Movement Disorders (physiopathology), Muscle, Skeletal (physiopathology), Neural Pathways (pathology), Neural Pathways (physiopathology), Neurodegenerative Diseases (pathology), Neurodegenerative Diseases (physiopathology), Nuclear magnetic resonance imaging, Volition (physiology).
- MESH :
- pathology : Basal Ganglia, Basal Ganglia Diseases, Cerebral Cortex, Movement Disorders, Neural Pathways, Neurodegenerative Diseases.
- physiology : Evoked Potentials, Somatosensory, Volition.
- physiopathology : Basal Ganglia, Basal Ganglia Diseases, Cerebral Cortex, Median Nerve, Movement Disorders, Muscle, Skeletal, Neural Pathways, Neurodegenerative Diseases.
- Aged, Body Image, Disease Progression, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging, Middle Aged.
Abstract
Two women (patient 1, 77 years old, and patient 2, 63 years old) with strong clinical evidence for corticobasal degeneration (CBD) are presented. Patient 2 was in an early stage of the disease with only a mild disability of her left hand. In addition to the clinical characteristics, both patients presented the typical cortical reflex myoclonus. Magnetic resonance imaging studies for both patients revealed nearly identical hyperintense lesions somatotopic from the left‐hand primary motor cortex (M1), extending to the midline and possibly supplementary motor area (SMA) in patient 2. To our knowledge, this has not been previously described in patients with CBD. These lesions may play a role in the etiology and the development of CBD with involvement of the M1 and may correspond to the underlying pathology of demyelination or gliosis.
Url:
DOI: 10.1002/1531-8257(199907)14:4<669::AID-MDS1018>3.0.CO;2-Y
Affiliations:
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Le document en format XML
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<term>Basal Ganglia (physiopathology)</term>
<term>Basal Ganglia Diseases (pathology)</term>
<term>Basal Ganglia Diseases (physiopathology)</term>
<term>Basal ganglion</term>
<term>Body Image</term>
<term>Brain (vertebrata)</term>
<term>Case study</term>
<term>Cerebral Cortex (pathology)</term>
<term>Cerebral Cortex (physiopathology)</term>
<term>Cerebral cortex</term>
<term>Cortical myoclonus</term>
<term>Corticobasal degeneration</term>
<term>Degeneration</term>
<term>Disease Progression</term>
<term>Evoked Potentials, Somatosensory (physiology)</term>
<term>Exploration</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Human</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Magnetic resonance imaging</term>
<term>Median Nerve (physiopathology)</term>
<term>Middle Aged</term>
<term>Movement Disorders (pathology)</term>
<term>Movement Disorders (physiopathology)</term>
<term>Muscle, Skeletal (physiopathology)</term>
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<term>Neural Pathways (physiopathology)</term>
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<term>Basal Ganglia Diseases</term>
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<term>Movement Disorders</term>
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<term>Neural Pathways</term>
<term>Neurodegenerative Diseases</term>
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<term>Body Image</term>
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<term>Follow-Up Studies</term>
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<front><div type="abstract" xml:lang="en">Two women (patient 1, 77 years old, and patient 2, 63 years old) with strong clinical evidence for corticobasal degeneration (CBD) are presented. Patient 2 was in an early stage of the disease with only a mild disability of her left hand. In addition to the clinical characteristics, both patients presented the typical cortical reflex myoclonus. Magnetic resonance imaging studies for both patients revealed nearly identical hyperintense lesions somatotopic from the left‐hand primary motor cortex (M1), extending to the midline and possibly supplementary motor area (SMA) in patient 2. To our knowledge, this has not been previously described in patients with CBD. These lesions may play a role in the etiology and the development of CBD with involvement of the M1 and may correspond to the underlying pathology of demyelination or gliosis.</div>
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